{"metadata":{"accession":"Q5BJB5","id":"Q5BJB5_DANRE","source_organism":{"taxId":"7955","scientificName":"Danio rerio","fullName":"Danio rerio (Zebrafish)"},"name":"Glycine cleavage system H protein","description":["The H protein shuttles the methylamine group of glycine from the P protein to the T protein","The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Has a pivotal role in the lipoylation of enzymes involved in cellular energetics such as the mitochondrial dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (DLAT), and the mitochondrial dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (DLST)"],"length":174,"sequence":"MAMCTVLRCVSVSLTSSLPRLSNINAHAPARLLARTCYRRSLSTNTPFCAALKFTDKHEWVRVDGGVATVGISNFAQEALGDVVYCGLPEIGAKLSQTDGFGALESVKAASELYSPLTGEVTDANDALADNPGLVNKSCYNDGWLMKMTVSIPEELDGLMDEAAYERYIKSIED","proteome":"UP000000437","gene":"gcsha","go_terms":[{"identifier":"GO:0019464","name":"glycine decarboxylation via glycine cleavage system","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005960","name":"glycine cleavage complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"676356c2fef36c74096b9603921b62087f9f9212","counters":{"domain_architectures":32373,"entries":16,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"cdd":1,"profile":1,"panther":1,"hamap":1,"ncbifam":2,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":32373}}}