{"metadata":{"accession":"Q47KE0","id":"Q47KE0_THEFY","source_organism":{"taxId":"269800","scientificName":"Thermobifida fusca (strain YX)","fullName":"Thermobifida fusca (strain YX)"},"name":"Pyruvate dehydrogenase E1 component subunit alpha","description":["The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)"],"length":365,"sequence":"MADTAKPKATGKTGSRRRAARNNADSHFNGEKPEVLLDYYRQMLLIRRFEERAAQAYTQARIGGYCHLNLGEEATIVGLMEALQERDYLFTNYREHGYAIAKGTHPREVMAELYGRSTGVSKGWGGSMHLFDARTRLLGGYGIVGGQLPLAVGAALAITYRGSDEVVMCQMGDGTTNIGAFHESLNIASLWNLPVIFVVINNFTGMGTPVERSSAEPELYKRGSAYRIEGVRVDGRDVLAVRDTATTLVERARSEHRPFLLEAFSYRMKGHSVVDPAKYRTKEEAEEALANDPIAMFEERLTEAGILTDEIKKEIAESVKAEVADAADFAENSPHPEVSTLFDYTYATPVANESRRMPADPVFAE","proteome":null,"gene":"pdhA","go_terms":[{"identifier":"GO:0016624","name":"oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004739","name":"pyruvate dehydrogenase (acetyl-transferring) activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006086","name":"pyruvate decarboxylation to acetyl-CoA","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0043231","name":"intracellular membrane-bounded organelle","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"cbe244fce9612c6647c66db75f1a2d8b87429a67","counters":{"domain_architectures":44056,"entries":10,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"cdd":1,"pfam":1,"panther":1,"ncbifam":1,"interpro":4},"proteome":0,"taxonomy":1,"similar_proteins":44056}}}