{"metadata":{"accession":"Q32PW8","id":"Q32PW8_DANRE","source_organism":{"taxId":"7955","scientificName":"Danio rerio","fullName":"Danio rerio (Zebrafish)"},"name":"Protein-L-isoaspartate O-methyltransferase domain-containing protein 1","description":["Substrate recognition component of an ECS (Elongin BC-CUL5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Specifically binds to the methyltransferase cofactor S-adenosylmethionine (AdoMet) via the N-terminal AdoMet binding motif, but does not display methyltransferase activity. May provide an alternate maintenance pathway for modified proteins by acting as a damage-specific E3 ubiquitin ligase adaptor protein"],"length":359,"sequence":"MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGNIHLSAPCIYSEVMEALKLQQGLSFLNLGSGTGYLSTMVGLIIGPFGVNHGVELHKDVVEYANERLDDFIKNSDSFDRFEFCEPHFVVGNCLEISSDSHQYDRIYCGAGVQKDHENYMKILLKVGGILVMPIEDQLTQIIRTGQSSWESKNILAVSFAPLVQQNRTDSNKSEAVVLPALSVRSLQDLSRIYIRRTLSSLINEENPNRTNTPRASQKHKRRRCRRRRRINTYVFVGNQLIPQPLDSEEDECIEEESKDEEQEKDIEPIKPEEPQVNHLRDKILSLPLPESLKAYLLYYRKK","proteome":null,"gene":"pcmtd1","go_terms":[{"identifier":"GO:0004719","name":"protein-L-isoaspartate (D-aspartate) O-methyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0036211","name":"protein modification process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"fd27f5d219e6daeaeb97fa24181997eac1119678","counters":{"domain_architectures":36346,"entries":6,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"panther":1,"pfam":1,"interpro":2},"proteome":0,"taxonomy":1,"similar_proteins":36346}}}