{"metadata":{"accession":"Q10446","id":"GID8_SCHPO","source_organism":{"taxId":"284812","scientificName":"Schizosaccharomyces pombe (strain 972 / ATCC 24843)","fullName":"Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)"},"name":"GID complex subunit 8","description":["Component of the GID E3 ligase complex recruiting N termini and catalyzing ubiquitination of proteins targeted for degradation. GID E3 is regulated through assembly with interchangeable N-degron-binding substrate receptors induced by distinct environmental perturbations. Required for the adaptation to the presence of glucose in the growth medium; mediates in association with the substrate receptor VID24/GID4 the degradation of enzymes involved in gluconeogenesis when cells are shifted to glucose-containing medium"],"length":240,"sequence":"MVGTSSLDISMSGSSSSDAEQWEKQTKSVHIDNSDVNSLILDYLVIQGDEEAAKTFAEEAQITDYYIPPYVKERLEICELIKSGSINSAICKLNELEPEILDTNSELLFELLRLRLLELIREVVEEKDTSDLAVERCLNFAHENLAPLAPSNQKFLNSLELTMSLLCFPPSSYSPALKNVLNYSQRERVANLANVSILKSQGLSNESRLLSLVNFERWCEKEAQRNSIEVQKFVPKASIK","proteome":"UP000002485","gene":"gid8","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"2e73de1ff3aa0698bae3821ac409afcc0fb436d7","counters":{"domain_architectures":4465,"entries":13,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"smart":3,"profile":2,"pfam":2,"panther":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":4465}}}