{"metadata":{"accession":"P58354","id":"SL2A8_BOVIN","source_organism":{"taxId":"9913","scientificName":"Bos taurus","fullName":"Bos taurus (Bovine)"},"name":"Solute carrier family 2, facilitated glucose transporter member 8","description":["Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate"],"length":478,"sequence":"MTPEDQEETQPLLRPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLRRAAPPAPHLDEDAASWFGAIVTLGAAAGGVLGGWLLDRAGRKLSLVLCALPFVAGFAVITAAQNLWMLLGGRLLTGLACGIASLVAPVYISEIAYPEVRGLLGSCVQLMVVTGILLAYLAGWVLEWRWLAVLGCVPPSFMLLLMCFMPETPRFLLSQHKHQEAMAAMQFLWGYAQGWEEPPLGAQHQDFHVAQLRRPGVYKPFIIGISLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTATAALIMDRAGRRLLLTLSGVVMVFSTSAFGTYFKLTEGGPSNSSHVDLPALVSMEAADTNVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGVCVLTNWFMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFGVLFTLACVPETKGKTLEQITAHFEGR","proteome":"UP000009136","gene":"SLC2A8","go_terms":[{"identifier":"GO:0022857","name":"transmembrane transporter activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0055085","name":"transmembrane transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":2,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"03fa97b454336937c9960a7f5034cde92ca2cdaa","counters":{"domain_architectures":276159,"entries":15,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"profile":1,"ncbifam":1,"panther":1,"pfam":1,"prints":1,"prosite":2,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":276159}}}