{"metadata":{"accession":"P53409","id":"ISL3_ONCTS","source_organism":{"taxId":"74940","scientificName":"Oncorhynchus tshawytscha","fullName":"Oncorhynchus tshawytscha (Chinook salmon)"},"name":"Insulin gene enhancer protein ISL-3","description":["Binds to one of the cis-acting domain of the insulin gene enhancer. May be involved in subtype specialization of primary motoneurons"],"length":363,"sequence":"MVDIIFNSSFLGDMGDHSKKKSGFAMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNLGFSSSDLVMRARDNVYHIECFRCSVCSRQLLPGDEFSLRDEELLCRADHSLLMERTSAGSPISPGHIHSNRSLHLAAEPVTVRAPHRNHVHKQSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMREQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQQQHSDKTVSIFSLQGLTGTPLVARSPIRHDNTVQGNSVEVQTYQPPWKALSEFALQSDLDQPAFQQLVPFSESGSLGNSSGSDVTSLSSHLPDTPNSMVPSPVET","proteome":"UP000694402","gene":"isl3","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000981","name":"DNA-binding transcription factor activity, RNA polymerase II-specific","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0045944","name":"positive regulation of transcription by RNA polymerase II","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0048665","name":"neuron fate specification","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0006355","name":"regulation of DNA-templated transcription","category":{"code":"P","name":"biological_process"}}],"protein_evidence":2,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"9df4db78da89de75c996e6971cfd5463e5e014f5","counters":{"domain_architectures":13971,"entries":22,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"profile":2,"smart":2,"cdd":3,"cathgene3d":2,"pfam":2,"panther":1,"prosite":2,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":13971}}}