{"metadata":{"accession":"P44689","id":"TILS_HAEIN","source_organism":{"taxId":"71421","scientificName":"Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)","fullName":"Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)"},"name":"tRNA(Ile)-lysidine synthase","description":["Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine"],"length":430,"sequence":"MDLLSDIEKQLQKATAQAFLIALSGGLDSTVLLSLFAKLCQKQPHLPPLSIRAIHIHHGLSPNADSWAKHCQDLCDQFQIPLIIERVQVDKTNGIEAGAREARYQAIKKYLQTQEMLVTAHHLNDQTETFFLALKRGSGLKGLGAMQQQSVLFGMPILRPLLGFTRTQLENYAQKEKLNWITDESNEDNRYDRNFLRNEILPELRERWAHFDLAVQRSAQHCFEQQQLINDLLSEIFTEHCQIKNQFKLCQFRQYSLAKQTALLRMWLAENQLEMPSKRQLTQLINDVIFAKEEANPQFQLVNKVIRRYQDSLYLTKPFSDLTKCTLKLEQNTLNLPDDLGNLTVQENEHNLIFYWQDYSVTLEKTNLPISIRFGYSGKVKHYPKRPREDIKKIWQELGVPPWERNRIPLIFYGNELKSAVGFFRVLKSS","proteome":"UP000000579","gene":"tilS","go_terms":[{"identifier":"GO:0000166","name":"nucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016879","name":"ligase activity, forming carbon-nitrogen bonds","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008033","name":"tRNA processing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"c26093a1662f5e9a451c7a1e4af9ff48ceec802b","counters":{"domain_architectures":7658,"entries":20,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":3,"pfam":3,"cdd":1,"smart":1,"panther":1,"hamap":1,"ncbifam":2,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":7658}}}