{"metadata":{"accession":"P20353","id":"GNAI_DROME","source_organism":{"taxId":"7227","scientificName":"Drosophila melanogaster","fullName":"Drosophila melanogaster (Fruit fly)"},"name":"G protein alpha i subunit","description":["Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Plays a role in glial cell differentiation during embryogenesis; loco, Galphao and the G-protein coupled receptor, moody, are required in the surface glia to achieve effective insulation of the nerve cord"],"length":355,"sequence":"MGCAVSTARDKEAIERSKNIDRALRAEGERAASEVKLLLLGAGESGKSTIVKQMKIIHDTGYSQEECEEYRRVVFSNTVQSLMVIIRAMGRLKIEFADPSRTDIARQFFTHASAADEGILLPEIVLLMKKLWADGGVQQSFARSREYQLNDSAGYYLNSLDRIAQPNYIPTQQDVLRTRVKTTGIIETHFSCKQLHFKLFDVGGQRSERKKWIHCFEGVTAIIFCVALSGYDLVLAEDEEMNRMIESLKLFDSICNSKWFVETSIILFLNKKDLFEEKIKRSPLTICFPEYTGTNTFEEAANYIRMKFENLNKRKDQKEIYTHLTCATDTNNVKFVFDAVTDVIIKNNLKQIGLF","proteome":"UP000000803","gene":"Galphai","go_terms":[{"identifier":"GO:0003924","name":"GTPase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019001","name":"guanyl nucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0031683","name":"G-protein beta/gamma-subunit complex binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0007165","name":"signal transduction","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005525","name":"GTP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007188","name":"adenylate cyclase-modulating G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"53ae36c3e9ecf4c3a6c7f817a0745ff8d4c5b7bc","counters":{"domain_architectures":40503,"entries":15,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"smart":1,"pfam":1,"profile":1,"ssf":2,"cdd":1,"cathgene3d":2,"panther":1,"prints":2,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":40503}}}