{"metadata":{"accession":"P09703","id":"US27_HCMVA","source_organism":{"taxId":"10360","scientificName":"Human cytomegalovirus (strain AD169)","fullName":"Human cytomegalovirus (strain AD169) (HHV-5)"},"name":"G-protein coupled receptor homolog US27","description":["Interacts with the host Gi complex without activating it, thereby probably interfering with the chemokine-Gi signaling (PubMed:35061538). May also function as a G protein sink to sequester G protein from the cell surface via internalization (PubMed:35061538). Plays an important role in spread of HCMV via the extracellular route"],"length":362,"sequence":"MTTSTNNQTLTQVSNMTNHTLNSTEIYQLFEYTRLGVWLMCIVGTFLNVLVITTILYYRRKKKSPSDTYICNLAVADLLIVVGLPFFLEYAKHHPKLSREVVCSGLNACFYICLFAGVCFLINLSMDRYCVIVWGVELNRVRNNKRATCWVVIFWILAVLMGMPHYLMYSHTNNECVGEFANETSGWFPVFLNTKVNICGYLAPIALMAYTYNRMVRFIINYVGKWHMQTLHVLLVVVVSFASFWFPFNLALFLESIRLLAGVYNDTLQNVIIFCLYVGQFLAYVRACLNPGIYILVGTQMRKDMWTTLRVFACCCVKQEIPYQDIDIELQKDIQRRAKHTKRTHYDRKNAPMESGEEEFLL","proteome":"UP000008992","gene":"US27","go_terms":[{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0004930","name":"G protein-coupled receptor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0007186","name":"G protein-coupled receptor signaling pathway","category":{"code":"P","name":"biological_process"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":false,"in_bfvd":false,"ida_accession":"587fa3dbe4504dc051049f3cca904dd9ab631b87","counters":{"domain_architectures":394800,"entries":10,"isoforms":0,"proteomes":1,"sets":1,"structures":2,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"profile":1,"pfam":1,"panther":1,"prosite":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":394800}}}