{"metadata":{"accession":"M3ZG06","id":"M3ZG06_XIPMA","source_organism":{"taxId":"8083","scientificName":"Xiphophorus maculatus","fullName":"Xiphophorus maculatus (Southern platyfish)"},"name":"DNA-directed DNA/RNA polymerase mu","description":["Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ)","Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells"],"length":502,"sequence":"MVPLKRRKVANSGSLNAGTHNSAATQPTKFPQVVLFLLERKMGASRRAFLSQLGRRKGFQVEELFSENVTHVICESNTAQEARMWLEAQGAGQAGRHLLDVSWYTESMRDGHPVEILDRHKLQEFAVNDSEVTPFSVPSYACQRRSTLKNHNAVLTDSLSLLAENAELSDEDGRGVAFRRAAAVLKALPSAVTKMSQLKGLPCLGEHSLRVIKDILENGASSEVESTKESERFKALKVLTGIFGVGSKTADRWIREGIHNLQQLRDSGQTLNRAQQAGLEHYDDIKQPVSLAEAEAIRGIVGRAVASVSPEAQIVLTGGFRRGKLTGHDVDFLITHPEEGSEVGLMPKLVSWLESQGLLLYQKTTRNSYLEGSEGPGRPPSNIDRFERCLSIFKLSAGQTGRGVQSEETAASPSAAERRWRAVRVDLVVSPISQFAFALLGWTGSKLFERELRRWAGHEKGMSLSSHALYDNKQGRYIRASSEEEIFAHLGLEFIPPTERNA","proteome":"UP000002852","gene":null,"go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003887","name":"DNA-directed DNA polymerase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0034061","name":"DNA polymerase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006281","name":"DNA repair","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005634","name":"nucleus","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0016779","name":"nucleotidyltransferase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"5fd7183be16cdf978797e5c747a48dff9c92f31e","counters":{"domain_architectures":4883,"entries":36,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":5,"profile":1,"ssf":4,"pfam":4,"smart":1,"cdd":1,"pirsf":2,"panther":1,"prosite":1,"prints":2,"interpro":14},"proteome":1,"taxonomy":1,"similar_proteins":4883}}}