{"metadata":{"accession":"M3Y8A1","id":"M3Y8A1_MUSPF","source_organism":{"taxId":"9669","scientificName":"Mustela putorius furo","fullName":"Mustela putorius furo (European domestic ferret)"},"name":"Protein O-mannosyl-transferase TMTC3","description":["Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response"],"length":916,"sequence":"MADINLKEITLIVGVVTACYWNSLFCGFVFDDVSAILDNKDLHPSTPLKTLFQNDFWGTPMSEERSHKSYRPLTVLTFRLNYLFSELKPMSYHLLNMIFHAVVSVIFLKVCKLFLDNKSSMIASLLFAVHPIHTEAVTGVVGRAELLSSIFFLAAFLSYTRSKGPDNSIVWTPIALTVVLVAVATLCKEQGITVVGICCVYEVFIAQGYTLPLLWTTAGQFFRGKSSIPFSMLQTLIKLIVLMFSTLLLVVIRVQVIQSQLPVFTRFDNPAAVSPTPTRQLTFNYLLPLNAWLLLNPSELCCDWTMGTIPLIESFLDIRNLATFTFFCFLGALGIFSLRYPGDSSKTVLMALCLMALPFIPASNLFFPVGFVVAERVLYVPSMGFCILVAHGWQKISNKSVLKKLSWICLSMVIFTHALKTLHRNWDWESEYTLFMSALKVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGAHMNVGRTYKNLNRTKEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAILMQESGEVKLRPEARKRLLSYINEEPQDANGYFNLGMLAMDDKKDSEAEMWMKKAIKLQADFRSALFNLALLYSQTAKELMALPILEELLRHYPDHIKGLILKGDILMNQKKDILGAKKCFEKILEMDPSNVQGKHNLCVVYFEEKDLLKAERCLVETLALAPHEEYIQRHLNIVRDKISSSSFAEQPISPAGKTSGVEGDKIPTENVQEDVKSEPRSTQIIKPSDNKSQSKSNKLLGKNTDKETPHKTTKEIKEIEKKRVAALKRLEEIERILNGE","proteome":"UP000000715","gene":"TMTC3","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"627782034039b5e271f7b91291b5d8db4259fe48","counters":{"domain_architectures":140,"entries":13,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"profile":3,"cathgene3d":1,"ssf":1,"pfam":3,"smart":1,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":140}}}