{"metadata":{"accession":"K2LRN7","id":"K2LRN7_HELPX","source_organism":{"taxId":"1145115","scientificName":"Helicobacter pylori R038b","fullName":"Helicobacter pylori R038b"},"name":"Bifunctional enzyme IspD/IspF","description":["Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)"],"length":401,"sequence":"MNGEAFKLSLESLEGDPFENKETLETLVKQTSVVLLAAGESKRFSQTIKKQWLRSNHTPLWLIVYESFKEALDFKEVILVVSGLDYVYIQRHYPKIKLVKGGASRQESVCNALKVIDSAYTLTSDVARGLANMETLKSLFLTLQQTSHYCIAPYLPCYDTAIYYNEALDREAIKLIQTPQLSHTKALQSALNQGDFKDESSAILQAFPNRVSYIEGSKDLHKLTTSGDLKHFAFFFNPAKDTFIGMGFDTHAFVKNKPMVLGGVVLDCEFGLKAHSDGDALLHAVIDAILGAIKGGDIGEWFPDNDPKYKNASSKELLKIVLDFSQSIGFELFEMGATIFSEIPKITPYKPAILENLSQLLGLEKSQISLKATTMEKMGFIGKQEGLLVQAHVSMRYQQKL","proteome":null,"gene":"ispDF","go_terms":[{"identifier":"GO:0070567","name":"cytidylyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008685","name":"2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016114","name":"terpenoid biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0050518","name":"2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008299","name":"isoprenoid biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"99e1dd050c8ea9c54af300699c83a6473cdf2290","counters":{"domain_architectures":4608,"entries":24,"isoforms":0,"proteomes":0,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"cdd":2,"ssf":2,"ncbifam":3,"hamap":2,"pfam":2,"panther":1,"prosite":2,"interpro":8},"proteome":0,"taxonomy":1,"similar_proteins":4608}}}