{"metadata":{"accession":"J3JUK5","id":"J3JUK5_DENPD","source_organism":{"taxId":"77166","scientificName":"Dendroctonus ponderosae","fullName":"Dendroctonus ponderosae (Mountain pine beetle)"},"name":"Eukaryotic translation initiation factor 3 subunit E","description":["Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation"],"length":440,"sequence":"MAKFDLTSKIGQYLDRHLVFPLLEFLSAKENYDETEVLKAKLDILSKTNMIDYAIDIRKQLYPRDEVPEDLKQRRQHVVAQLQELQQVVEPILQIMANEDIMKNMENLRDSKTLIAYLEKEVRFDMDMINSLHALAKYRYECGNYSVSTSYLYFCMLVLPPSDKNYLSALWGKFASEILVQNWDSALEDLNKLREHIDNSPHQYGGSMLNLLQQRTWLIHWSLFVFFNHAMGRELIIEMFLYRPHYLNAIQTMCPHILRYLATAVIINRGRRSALKDLVKVIQQESYTYRDPITEFLEHLYVNFDFDGARQKLRECETVLFNDFFLISCLDEFVENARLMIFETFCRIHQCISIGMLAEKLNMNPDEAECWIVNLIRNARLDAKIDSKLGHVVMGAQPMSPYQQLIEKIDSLSVRSETLSALIDRKLKAKTDLRWGPQEF","proteome":null,"gene":null,"go_terms":[{"identifier":"GO:0003743","name":"translation initiation factor activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0005852","name":"eukaryotic translation initiation factor 3 complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"c4806a904b5eadf37b5ba070f4c9239c098f487d","counters":{"domain_architectures":1276,"entries":14,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cdd":1,"pfam":2,"smart":2,"profile":1,"ssf":1,"panther":1,"pirsf":1,"hamap":1,"interpro":4},"proteome":0,"taxonomy":1,"similar_proteins":1276}}}