{"metadata":{"accession":"H3A6M7","id":"H3A6M7_LATCH","source_organism":{"taxId":"7897","scientificName":"Latimeria chalumnae","fullName":"Latimeria chalumnae (Coelacanth)"},"name":"ATP-binding cassette sub-family D member 3","description":["Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation"],"length":658,"sequence":"MAAFSRYLTAKNSSIAGAALLLLYLLNKRRGSSSSKKSGKTQVIQNNEKDGKKEKAVVDRVFFARIWTILKIMVPRMCSKESGYLLLIAAMLVARTYCDVWMIQNGTMIESGIISRNCKLFKEHFFRFTAAMPLISLINNFLKLGLNELKLRFRVRLTRYLYEEYLKGYTYYKMGNLDNRIANADQLLTQDVEKFCNSVVDLYSNLSKPLLDICLYIFKLTSAIGAQGPASMMAYLIVSGLFLTRLRRPIGKMTITEQRYEGEYRYVNSRLITNSEEIAFYNGNRREKQTIYTTFQKLVDHLHNFILFRFSMGFVDSIIAKYLATVVGYLVVSRPFLNLLHPRHMKSTHAELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNTGKYERTMISQQEKGTNAQQLQPLIPGSGRIYNLDNIIKFDHVPLATPNGDILIRDLSFEVKSGANVLVCGPNGCGKSSLFRVLGELWPLFGGNLTKPDRGKLFYVPQRPYMTLGTLRDQVIYPDTVEDQNRKGVTDQVLKEYLDNVQLGQILEREGGWDTVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEFYLHMDGRGKYDFKKITEETVEFGS","proteome":"UP000008672","gene":"ABCD3","go_terms":[{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0140359","name":"ABC-type transporter activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0055085","name":"transmembrane transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016887","name":"ATP hydrolysis activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005324","name":"long-chain fatty acid transmembrane transporter activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0042626","name":"ATPase-coupled transmembrane transporter activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0015910","name":"long-chain fatty acid import into peroxisome","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005777","name":"peroxisome","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"7d63b8933b00a43572cacec89714035b15328362","counters":{"domain_architectures":17112,"entries":21,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":2,"profile":2,"cdd":1,"pfam":2,"smart":1,"panther":1,"ncbifam":1,"prosite":1,"interpro":8},"proteome":1,"taxonomy":1,"similar_proteins":17112}}}