{"metadata":{"accession":"H2XZ76","id":"H2XZ76_CIOIN","source_organism":{"taxId":"7719","scientificName":"Ciona intestinalis","fullName":"Ciona intestinalis (Transparent sea squirt)"},"name":"DNA replication complex GINS protein PSF1","description":["Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built","Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA"],"length":195,"sequence":"MFGEKALDLIREVHRTREGSLGPYNEDGVRQVLEEMQVLYEANQQDVAQLVQNDSDQTSLTAVQIRHDSLQRNKRCLLAYLYNRLQKIRALRWEFGSVLPTDVRGNMSPKEIEWFTKYNRALANYMRSLGNGGLDLTQDLHPPQNVHIEVRCVEDKGELELDDGSKILLKKNSLHYLPRSQCEHLIRQGVLKHVT","proteome":"UP000008144","gene":"LOC100182896","go_terms":[{"identifier":"GO:0006260","name":"DNA replication","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000811","name":"GINS complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"0a6e7fca5ebfeed72c6e0ddbcc49892f88dd5056","counters":{"domain_architectures":3493,"entries":11,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"cdd":2,"pfam":2,"panther":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":3493}}}