{"metadata":{"accession":"H2V3V0","id":"H2V3V0_TAKRU","source_organism":{"taxId":"31033","scientificName":"Takifugu rubripes","fullName":"Takifugu rubripes (Japanese pufferfish)"},"name":"Stress-activated protein kinase JNK","description":["Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity","Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. May play a role in the regulation of the circadian clock"],"length":384,"sequence":"MNRNKREKEYYSIDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDHNLERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGLLMTPYVVTRYYRAPEVILGMGYQANVDVWSVGCIMAEMVRGSVLFPGTDHIDQWNKVIEQLGTPSQEFLMKLNQSVRTYVENRPRYAGYTFEKLFPDVLFHADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPTEVEAPPPAITDKQLDEREHTVEEWKELIYKEVLDWEERTKNGVIKGQPASIAQVQQ","proteome":"UP000005226","gene":"mapk8b","go_terms":[{"identifier":"GO:0004672","name":"protein kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006468","name":"protein phosphorylation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004707","name":"MAP kinase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"726173b0dde7bbc50c5d845a39c992d18faf18f3","counters":{"domain_architectures":887312,"entries":17,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cdd":1,"smart":1,"profile":1,"pfam":1,"cathgene3d":2,"panther":1,"prints":1,"prosite":2,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":887312}}}