{"metadata":{"accession":"H0YVF6","id":"H0YVF6_TAEGU","source_organism":{"taxId":"59729","scientificName":"Taeniopygia guttata","fullName":"Taeniopygia guttata (Zebra finch)"},"name":"Solute carrier family 2, facilitated glucose transporter member 1","description":["Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. Required for mesendoderm differentiation"],"length":489,"sequence":"MDTGSKMTARLMLAVGGAVLGSLQFGYNTGVINAPQKVIEDFYNRTWLYRYEEPISPATLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMSNILAFVAAVLMGFSKMAFSFEMLILGRFIIGLYSGLTTGFVPMYVGEVSPTALRGALGTFHQLGIVLGILIAQVFGLDLIMGNDSLWPLLLGFIFVPALLQCIILPFAPESPRFLLINRNEENKAKSVLKKLRGTTDVSSDLQEMKEESRQMMREKKVTIMELFRSPMYRQPILIAIVLQLSQQLSGINAVFYYSTSIFEKSGVEQPVYATIGSGVVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALTLLDQMPWMSYLSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAFAVAGLSNWTSNFIVGMGFQYIAQLCGSYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQSGGGQSDKTPDEFHSLGADSQ","proteome":"UP000007754","gene":"SLC2A1","go_terms":[{"identifier":"GO:0022857","name":"transmembrane transporter activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0055085","name":"transmembrane transport","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0055056","name":"D-glucose transmembrane transporter activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:1904659","name":"D-glucose transmembrane transport","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"03fa97b454336937c9960a7f5034cde92ca2cdaa","counters":{"domain_architectures":276159,"entries":18,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"cdd":1,"profile":1,"ssf":1,"panther":1,"ncbifam":1,"pfam":1,"prosite":2,"prints":2,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":276159}}}