{"metadata":{"accession":"H0W631","id":"H0W631_CAVPO","source_organism":{"taxId":"10141","scientificName":"Cavia porcellus","fullName":"Cavia porcellus (Guinea pig)"},"name":"Sulfotransferase","description":["Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Catalyzes with a lower efficiency the sulfation of Gal residues of keratan sulfate, another glycosaminoglycan. Can also catalyze the sulfation of the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen"],"length":473,"sequence":"MEKGLAVAQDCWDFAHSLRMRSKYALFLAFVVIVFIFIEKENKIISRVSHRLKQIPQSLADANGTDPALILAENASLLSLSELDSAFSQLQSRLHNLSLQLGVEPASKEAPVAAEPSQPASAPRQQRRHVLLMATTRTGSSFVGEFFNQQGNIFYLFEPLWHIERTVAFEQRGSSAAGSALVYRDVLQQLFLCDLYVLEPFISPVPEAHLTQFMFRRGSSRSLCEDPVCTPFVKKVFEKYHCKDRRCGPLNVTLAAEACRRKDHMALKAVRIRQLEFLKPLAEDPRLDLRVIQLVRDPRAVLASRIVAFAGKYETWKKWLAEGQDQLQEEEVQRLRGNCESIRLSAELGLRQPAWLRGRYMLVRYEDVARSPLQKAREMYRFAGIPLTPQVEEWIQKNTQAALDSSGIYSTQKNSSEQFEKWRFSMPFKLAQVVQAACASTMRLFGYKLAKDAASLTNRSISLLEERGTFWVT","proteome":"UP000005447","gene":"CHST3","go_terms":[{"identifier":"GO:0008146","name":"sulfotransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005975","name":"carbohydrate metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000139","name":"Golgi membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"c3f904adb28054815298b5a4924ad2c008edc08c","counters":{"domain_architectures":55737,"entries":9,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"panther":1,"pirsf":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":55737}}}