{"metadata":{"accession":"G7WTU7","id":"G7WTU7_9INFB","source_organism":{"taxId":"1031467","scientificName":"Influenza B virus (B/Managua/1499.02/2010)","fullName":"Influenza B virus (B/Managua/1499.02/2010)"},"name":"Non-structural protein 1","description":["Binds and inhibits the conjugation of the ubiquitin-like G1P2/ISG15 protein to its target proteins. Since G1P2/ISG15 is an early antiviral protein, NS1 may inhibit the host antiviral response. Prevents EIF2AK2/PKR activation, either by binding double strand RNA or by interacting directly with EIF2AK2/PKR. Also binds poly(A) and U6 snRNA"],"length":282,"sequence":"MANNNMTTTQIEVGPGATNATINFEAGILECYERLSWQRALDYPGQDRLNRLKRKLESRIKTHNKSEPESKRMSLEERKAIGVKMMKVLLFMNPSAGIEGFEPYCMKSSSNSNCTKYNWTDYPSTPGRCLDDIEEEPEDVDGPTEIVLRDMNNKDARQKIKEEVNTQKEGKFRLTIRRDMRNVLSLRVLVNGTFLKHPNGYKSLSTLHRLNAYDQSGRLVAKLVATDDLTVEDEEDGHRILNSLFERLNEGHSKPIRAAETAVGVLSQFGQEHRLSPEEGDN","proteome":null,"gene":"NS1","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":false,"in_bfvd":false,"ida_accession":"93d2301ee5fb2d52da650e32be4af5e1c3b1f258","counters":{"domain_architectures":8870,"entries":7,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"pirsf":1,"hamap":1,"interpro":2},"proteome":0,"taxonomy":1,"similar_proteins":8870}}}