{"metadata":{"accession":"G3UZ30","id":"G3UZ30_MOUSE","source_organism":{"taxId":"10090","scientificName":"Mus musculus","fullName":"Mus musculus (Mouse)"},"name":"E3 ubiquitin-protein ligase PPP1R11","description":["Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1"],"length":120,"sequence":"MEWVRVKAEEMRKQENKENQSLTMKLRKRKPEKKVEWSSDTVDNEHMGRRSSKCCCIYEKPRAFGESSTESDEDEEEGCSHKHCVRGHRKGRRPTTPAPTPTTPPQPPDPSKPPPGPMQH","proteome":"UP000000589","gene":"Ppp1r11","go_terms":[{"identifier":"GO:0004865","name":"protein serine/threonine phosphatase inhibitor activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":1,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"ad1dc68d26dcd895052b0b779c65d3d2b59110c7","counters":{"domain_architectures":3700,"entries":3,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"panther":1,"pfam":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":3700}}}