{"metadata":{"accession":"G3TG89","id":"G3TG89_LOXAF","source_organism":{"taxId":"9785","scientificName":"Loxodonta africana","fullName":"Loxodonta africana (African elephant)"},"name":"Protein FAM162A","description":["Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly"],"length":144,"sequence":"GSFFRLCERDVSSSLRLTRNTDLKRGNGLCTKPQESPKAPSDSYSHRVPLHKPTEWERKILVWSGRFKKEEEIPEAVSFEMLDTAKNKIRIKVSYLMIALTLAGCVVMIAEGKKAIKRQESLTSVNLEKKAHLREEAATKAKAE","proteome":"UP000007646","gene":"FAM162A","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"1b48ad22e090a49f381d6b6a795f3eaeacb3a5ba","counters":{"domain_architectures":2437,"entries":3,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"panther":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":2437}}}