{"metadata":{"accession":"G3QJB9","id":"G3QJB9_GORGO","source_organism":{"taxId":"9595","scientificName":"Gorilla gorilla gorilla","fullName":"Gorilla gorilla gorilla (Western lowland gorilla)"},"name":"Serine/threonine-protein kinase Nek11","description":["Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation"],"length":540,"sequence":"MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFMEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLTCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLRELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALAWCLENVLGCTSLDTKTITTMAEDMSPGPPIFNSAMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPRASDCFEVDQLLYFEEQLLITMGKEPTLQNHL","proteome":"UP000001519","gene":"NEK11","go_terms":[{"identifier":"GO:0004672","name":"protein kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006468","name":"protein phosphorylation","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"726173b0dde7bbc50c5d845a39c992d18faf18f3","counters":{"domain_architectures":887312,"entries":11,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"smart":1,"pfam":1,"profile":1,"panther":1,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":887312}}}