{"metadata":{"accession":"G1KZF9","id":"G1KZF9_AILME","source_organism":{"taxId":"9646","scientificName":"Ailuropoda melanoleuca","fullName":"Ailuropoda melanoleuca (Giant panda)"},"name":"non-specific serine/threonine protein kinase","description":["Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation"],"length":254,"sequence":"MAAASAAAAAEKNDEPAPEAEALAAARERSSRFLSGLELVKQGAEARVFRGRFQGRAAVVKHRFPKGYRHPALEARLGRRRTVQEARALLRCRRAGISAPVVFFVDYASNCLYMEEIEGSVTVRDYIQSTVETENTPQSLLGLARTVGQVLARMHDEDLIHGDLTTSNMLLKPPVEQLNIVLIDFGLSFISALPEDKGVDLYVLEKAFLSTHPNTETVFEAFLKSYATFSKKSKPVLKKLDEVRLRGRKRSMVG","proteome":"UP000008912","gene":"TP53RK","go_terms":[{"identifier":"GO:0004672","name":"protein kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006468","name":"protein phosphorylation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004674","name":"protein serine/threonine kinase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"1a5aef97ef5001f4e0f71c8229f6da9cfadb22cb","counters":{"domain_architectures":12757,"entries":13,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"smart":1,"profile":1,"ssf":1,"cathgene3d":2,"panther":1,"ncbifam":1,"pfam":1,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":12757}}}