{"metadata":{"accession":"F9NYQ4","id":"F9NYQ4_STROR","source_organism":{"taxId":"768726","scientificName":"Streptococcus mitis bv. 2 str. F0392","fullName":"Streptococcus mitis bv. 2 str. F0392"},"name":"Beta sliding clamp","description":["Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication"],"length":378,"sequence":"MIHFSINKNLFLQALNTTKRAISSKNAIPILSTIKIDVTNEGITLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQKQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLVLETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNGDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFDVVNLRQSMERARLLSSATQNGTVKLEIKGGVVSAHVHSPEVGKVNEEIDTEQVTGDDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN","proteome":null,"gene":"dnaN","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003887","name":"DNA-directed DNA polymerase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008408","name":"3'-5' exonuclease activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006260","name":"DNA replication","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0009360","name":"DNA polymerase III complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"bfad543c1c3a99ab704fbd29a259ed902f9a9bab","counters":{"domain_architectures":26841,"entries":16,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"pfam":3,"ssf":1,"cdd":1,"cathgene3d":2,"smart":1,"panther":1,"pirsf":1,"ncbifam":1,"interpro":5},"proteome":0,"taxonomy":1,"similar_proteins":26841}}}