{"metadata":{"accession":"F7BQU5","id":"F7BQU5_ORNAN","source_organism":{"taxId":"9258","scientificName":"Ornithorhynchus anatinus","fullName":"Ornithorhynchus anatinus (Duckbill platypus)"},"name":"Tyrosine-protein kinase","description":["Non-receptor tyrosine-protein kinase which phosphorylates DOK1 on tyrosine residues. Also phosphorylates KHDRBS1/SAM68 and VIM on tyrosine residues. Phosphorylation of KHDRBS1 is EGF-dependent. Phosphorylates OTUB1, promoting deubiquitination of RPTOR"],"length":498,"sequence":"MEPFLRKRLTFLSFFWNKLWPTEIPDDCIPRYPGPDPVTMDLDPDPDPVSSQPGSPSSTVLFTALYDFTARCADELSVNRGDKLFAIKEEGDYIFARRLSGRPSTGLVPINYVAKATHESFSTQPWFFGGISRSEAQQLLLSPSNQHGAFLVRPSESSRGDYSLSVRTKAKVCHYRISKAPDGGLYIQKGQVFPSLEELLAFYKANWKIIQNPLLKPCIPERPPERDEWERPRSEFALRRKLGEGYFGEVWEGLWLNMVPVAIKIIKQADMRLDDFTKEIQNLKSLKHEKLIRLHAVCSIGEPVYIVTELMRKGNLQNYLNSPEGKTLSLIHLMSIACQVVEGMTYLEEKHIVHRDLAARNILVGDDLTCKIADFGLARLLKDDIYSTSSSTKIPVKWTAPEAANYRIYSQKSDVWSFGILLYEVFTFGQCPYEGMTNQETIHQITRGYRLPRPNTCSPEVYVIMLECWKANAEERPTFFTLREKLNSIYRRVYHSFT","proteome":"UP000002279","gene":"SRMS","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004713","name":"protein tyrosine kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006468","name":"protein phosphorylation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004672","name":"protein kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"be4dfe707ccb04aaf2be502362dd8b9b26605686","counters":{"domain_architectures":603,"entries":34,"isoforms":0,"proteomes":1,"sets":5,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"profile":3,"smart":3,"cdd":2,"ssf":3,"pfam":3,"panther":1,"prints":3,"prosite":2,"interpro":11},"proteome":1,"taxonomy":1,"similar_proteins":603}}}