{"metadata":{"accession":"F4QCS7","id":"F4QCS7_CACFS","source_organism":{"taxId":"261658","scientificName":"Cavenderia fasciculata","fullName":"Cavenderia fasciculata (Slime mold)"},"name":"Core Histone H2A/H2B/H3 domain-containing protein","description":["Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling"],"length":137,"sequence":"MARTKQTARKSTGAKVPRKHIGSKQAHKQTPVSSGGVKKVHRFHPGTVALREIRKYQKSTDLLIRKLPFQRLVREIAQEFKTDLRFQSAAIAALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERT","proteome":"UP000007797","gene":"H3a","go_terms":[{"identifier":"GO:0046982","name":"protein heterodimerization activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0030527","name":"structural constituent of chromatin","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0000786","name":"nucleosome","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"e204a9d55ad7bafe2e507ca80f663a0ac2378352","counters":{"domain_architectures":87265,"entries":11,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"smart":1,"cdd":1,"pfam":1,"panther":1,"prints":1,"prosite":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":87265}}}