{"metadata":{"accession":"F3PXZ3","id":"F3PXZ3_9BACE","source_organism":{"taxId":"763034","scientificName":"Bacteroides fluxus YIT 12057","fullName":"Bacteroides fluxus YIT 12057"},"name":"Multifunctional fusion protein","description":["Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism","Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor","Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism, and the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA)"],"length":748,"sequence":"MTVNELKAIVLQGGSLKEEQAEWLATQPDKEALYEAAHGITKALASEEFDMCSIINAKSGRCPENCKWCAQSAHYKTQADVYDLVGKEECLRHARHNEEQGVARFSLVTSGRKPSSKNMEKLCEAARHMRKHSSIQLCASLGLLDEEEMRALHEAGITRYHCNLETAPSYFPHLCSTHSQEDKLRTLKAARNAGMDICSGGIIGMGESMQQRIEFAFTLKNLEVQSIPINLLSPIPGTPLEKQEPLSEEEILTTIALFRFINPTAFLRFAGGRSQLSKEAVKKALHIGINSAIVGDLLTTLGSKVSEDKVLIEEAGYRFSDSQFDREHLWHPYTSTTHPLPVYKVKQAEGATITLESGQTLIEGMSSWWCAVHGYNHPVLNRAAEEQLRKMSHVMFGGLTHDPAIELGKLLLPLVPPSMQKIFYADSGSVAVEVALKMAVQYWYGKGKEKKNNFVTIRSGYHGDTWNAMSVCDPVTGMHSLFGPSLPVRHFVPQPSSRFNGEWNPEDLLPLKETIERHHDELAALILEPIVQGAGGMWFYHPQYLREAARLCKEYNLLLIFDEIATGFGRTGKLFAWEHAGVEPDIMCIGKALTGGYMTLSAVLTTNEVADTISNHSPGAFMHGPTFMGNPLACAVACASVRLLTSPEYDWQGKVNRISRQLQEELAPAWELPSVNDVRVLGAIGVIETKTPVDMAWMQRRFVEEGIWVRPFGKLVYLMPPFIIEPEQLTKLTRGLMNSLTPEEVRQN","proteome":"UP000003416","gene":"bioB","go_terms":[{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051536","name":"iron-sulfur cluster binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0030170","name":"pyridoxal phosphate binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004076","name":"biotin synthase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009102","name":"biotin biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004015","name":"adenosylmethionine-8-amino-7-oxononanoate transaminase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"899987c73b73596e0b8b6e05eb28dfd2b150480d","counters":{"domain_architectures":219,"entries":36,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cathgene3d":3,"profile":1,"smart":2,"cdd":2,"pfam":3,"sfld":3,"hamap":2,"ncbifam":4,"panther":1,"prosite":1,"interpro":12},"proteome":1,"taxonomy":1,"similar_proteins":219}}}