{"metadata":{"accession":"E4ZDM7","id":"E4ZDM7_NEIL0","source_organism":{"taxId":"489653","scientificName":"Neisseria lactamica (strain 020-06)","fullName":"Neisseria lactamica (strain 020-06)"},"name":"tRNA-dihydrouridine(16) synthase","description":["Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs"],"length":333,"sequence":"MIDGQTNKPEQKTRIILAPMQGLVDDVMRDLLTRIGGYDECVSEFVRITHTVHSRATWLKYVPEIANGNKTPVGTPCTVQLLGSDADNMAANALEAIRFGADKIDLNFGCPAPTVNRHKGGAILLKEPQLIFHIVKTLRERLPAHIPLTAKMRLGYEDKSRALECACAIAEGGACGLTVHARTKAEAYEPPAHWEWIKKIRDAVNIPVTANGDVFTLQDYIGIKTISGCNSVMLGRGAVIRPDLARQIKQYESGLSVRDTDFAEISKWIRLFFDLCLAKEANNKYPPARLKQWLGMMKKEFAAAQNLFDRIRTVKDADEVRNILAAFEREMNT","proteome":null,"gene":"dusC","go_terms":[{"identifier":"GO:0017150","name":"tRNA dihydrouridine synthase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0050660","name":"flavin adenine dinucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008033","name":"tRNA processing","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0002943","name":"tRNA dihydrouridine synthesis","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"472d8faf270aff0fc25e3ad6bc9e20ee1e59630e","counters":{"domain_architectures":57766,"entries":15,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"cdd":1,"ssf":1,"pfam":1,"pirsf":1,"panther":1,"hamap":1,"prosite":1,"interpro":6},"proteome":0,"taxonomy":1,"similar_proteins":57766}}}