{"metadata":{"accession":"D5DSY8","id":"D5DSY8_PRIM1","source_organism":{"taxId":"545693","scientificName":"Priestia megaterium (strain ATCC 12872 / QMB1551)","fullName":"Priestia megaterium (strain ATCC 12872 / QMB1551)"},"name":"5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase","description":["Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine"],"length":231,"sequence":"MKVAIIGAMEEEVTILRDKIENRQETVIAGCEYSTGTISGVEVVLLKSGIGKVNAALSTAILLEKFKPDYVINTGSAGGFHPELNVGDAVISTEVRHHDVDVTVFNYEYGQVPNLPAAFKADDKLVRLAEESALEVTDMKIVKGLIATGDSFMNDPVRVEFVRSKFPDLYAAEMEAAAVAQVCYQFGVPFVILRALSDIAGKESNVSFEQFLEKAAVNSTKLVLNFITKLK","proteome":"UP000000935","gene":"mtnN","go_terms":[{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009116","name":"nucleoside metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0008782","name":"adenosylhomocysteine nucleosidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008930","name":"methylthioadenosine nucleosidase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009164","name":"nucleoside catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0019509","name":"L-methionine salvage from methylthioadenosine","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"27552274e8941821ae0d138350daef5fe3adde72","counters":{"domain_architectures":85785,"entries":11,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"pfam":1,"cdd":1,"ncbifam":2,"panther":1,"hamap":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":85785}}}