{"metadata":{"accession":"D5CZH2","id":"RUTA_ECOKI","source_organism":{"taxId":"714962","scientificName":"Escherichia coli O18:K1:H7 (strain IHE3034 / ExPEC)","fullName":"Escherichia coli O18:K1:H7 (strain IHE3034 / ExPEC)"},"name":"Pyrimidine monooxygenase RutA","description":["Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo"],"length":393,"sequence":"MQTSHYAAEKDMQDAAPRLTFTLRDEERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGSGKSDFKGDFFTMDDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIENFGERIQPLMQCRAHLPALTQEVA","proteome":null,"gene":"rutA","go_terms":[{"identifier":"GO:0016705","name":"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004497","name":"monooxygenase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006212","name":"uracil catabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"5fa18b3d0fe8c4cadc1b24f85bdfa6c4345d05ec","counters":{"domain_architectures":182008,"entries":11,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"cdd":1,"pfam":1,"ssf":1,"panther":1,"ncbifam":1,"hamap":1,"interpro":4},"proteome":0,"taxonomy":1,"similar_proteins":182008}}}