{"metadata":{"accession":"C4IB41","id":"C4IB41_CLOBU","source_organism":{"taxId":"632245","scientificName":"Clostridium butyricum E4 str. BoNT E BL5262","fullName":"Clostridium butyricum E4 str. BoNT E BL5262"},"name":"dihydrouracil dehydrogenase (NAD(+))","description":["Involved in pyrimidine base degradation. Catalyzes physiologically the reduction of uracil to 5,6-dihydrouracil (DHU) by using NADH as a specific cosubstrate. It also catalyzes the reverse reaction and the reduction of thymine to 5,6-dihydrothymine (DHT)"],"length":362,"sequence":"MNLNTTIGKIKLENPLMPASGPLVGDKDKMSALNEFGVGAMVTKTISSKKAEVVRPCIYGGKNFIMNAELWSEYAPEVWIDEFLPSIKKELKDKPLIISVGYTKEDMEFLIPKLDVFADAFEISTHYVGKDLSNIKETLKTIRRFTQKPVFMKMSPHIPDPIGFAKMVIENKGSGIVAINSLGPTMNIDIDKRSVLIGNKEGEVWTSGPAIKPMALALIHKIKKAVPECEIIGVGGISSADDIIEFLLAGASAVQMLSAAMLKGKDLYEKLIEELPKALKKHGFNSVEEVINEKLSIGQVKYEPEYPLINKDKCTNCRLCEKACPYFAITSIDNQIKIDTKNCFGCGLCESRCPSKAIYNVF","proteome":"UP000003081","gene":"CLP_0393","go_terms":[{"identifier":"GO:0016627","name":"oxidoreductase activity, acting on the CH-CH group of donors","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"9b394982993580a5a96612cb117e0a00c5ac2a94","counters":{"domain_architectures":150,"entries":15,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"pfam":2,"cathgene3d":3,"profile":1,"panther":1,"prosite":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":150}}}