{"metadata":{"accession":"C2KWZ0","id":"C2KWZ0_9FIRM","source_organism":{"taxId":"585501","scientificName":"Oribacterium sinus F0268","fullName":"Oribacterium sinus F0268"},"name":"dITP/XTP pyrophosphatase","description":["Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions"],"length":436,"sequence":"MRILFATHNQHKLREIQEILSNFPGTILCAKDLGMDQEVEENGTSFLENAEIKARALYNFAKAQGLLEEDDLVMADDSGLSIEALSFGPGIYSARFLGVDTPYPEKNRRILAMMEESSSKSRMAYFSCAIVAIFADGKLLQTEARCTGEIAKEPGGEEGFGYDPIFYLPEYRKTAAELSREEKNKVSHRGKALRKMERMIQEEQEKRDSARFSKAGQEQSGKGKEAKAEHKAEKDSGENPEKEEDAEKGQKLVEKGQEAAREAKTKIAGRIDPSSEEKILVLSDNHRRLDYVEKVLRLHPDISMCIHLGDSEGEGEVQALLPKGCESYFVQGNNDFFSYLPKDVEVRIGKERCFLTHGHLYGVNFGLERLSEEARDRNCSMAFFGHTHKPCNKVVNGVHCINPGSISFPRQEDRRPCYSLLFLDQKGNLRVEMHKI","proteome":"UP000004121","gene":"rdgB","go_terms":[{"identifier":"GO:0047429","name":"nucleoside triphosphate diphosphatase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009143","name":"nucleoside triphosphate catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0017111","name":"ribonucleoside triphosphate phosphatase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"8b776d26e33713e3662461b8e4660bcd9ff1ba90","counters":{"domain_architectures":6,"entries":17,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cathgene3d":2,"cdd":1,"pfam":2,"hamap":1,"ncbifam":2,"panther":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":6}}}