{"metadata":{"accession":"C1BSG8","id":"C1BSG8_LEPSM","source_organism":{"taxId":"72036","scientificName":"Lepeophtheirus salmonis","fullName":"Lepeophtheirus salmonis (Salmon louse)"},"name":"non-specific serine/threonine protein kinase","description":["Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP. Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation"],"length":219,"sequence":"MNLENYSLMAQGAESRLYLGSYLGKDVIIKHRFSKKYRHPDLDSRLIKEHSKAEVRCLIRCQNAGINTPTIYYADDSFVVLEYLKTASRCRDVVDKYLKANDSEGLGKLAKSMGFVIGNLHKNNIIHGDLTTSNILVDTNGEIYLIDFGLGQVEGNAEDKGVDVYVLERALLSTHPQYTEDLFNIFLESYRSQLGKQAKDVIKKYEEIRLRGRKRSMEG","proteome":null,"gene":"PRPK","go_terms":[{"identifier":"GO:0004672","name":"protein kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006468","name":"protein phosphorylation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004674","name":"protein serine/threonine kinase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":2,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"0c53e084e615dc123578ed813911712baf3c7947","counters":{"domain_architectures":13633,"entries":15,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"smart":1,"profile":1,"ssf":1,"cathgene3d":2,"pfam":1,"panther":1,"ncbifam":2,"prosite":1,"interpro":5},"proteome":0,"taxonomy":1,"similar_proteins":13633}}}