{"metadata":{"accession":"B8NDR9","id":"B8NDR9_ASPFN","source_organism":{"taxId":"332952","scientificName":"Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167)","fullName":"Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 / SRRC 167)"},"name":"Acireductone dioxygenase","description":["Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway"],"length":178,"sequence":"MKAYWYDNKPGDQREPHDSGRPVSKDYLASLGVFYRYCPDIESVNALAKERGYKNRDEVCVSPQTMGDVYESKVKMFFAEHLHEDEEIRYIRDGEGYFDVRGQDDEWVRIQLSKDDLIILPAGIYHRFTTDEKNYVKAMRLFQEEPKWTPLNRSEDVDTNPHRKTYLGTLSTSAVAAK","proteome":"UP000596276","gene":"ADI1","go_terms":[{"identifier":"GO:0010308","name":"acireductone dioxygenase (Ni2+-requiring) activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0010309","name":"acireductone dioxygenase [iron(II)-requiring] activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016491","name":"oxidoreductase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019509","name":"L-methionine salvage from methylthioadenosine","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"552e74f4cc2d23d46b226a6ad8c8614d3ba679cf","counters":{"domain_architectures":9941,"entries":10,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"cdd":1,"hamap":1,"panther":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":9941}}}