{"metadata":{"accession":"A9A799","id":"ADHS_METM6","source_organism":{"taxId":"444158","scientificName":"Methanococcus maripaludis (strain C6 / ATCC BAA-1332)","fullName":"Methanococcus maripaludis (strain C6 / ATCC BAA-1332)"},"name":"2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase","description":["Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids"],"length":272,"sequence":"MKMFDNIKNVGKLIRLERIFDKNSEKTVIIPMDHGVSSGPLDGIKDMRITTNAVADGGANAVLGHKGLVRHGHRGYGRDIGLIIHMSAGTSISPDPNKKVIVTTVEDAIRLGADAVSLHVNVGAETDFEMYRDLGLISETCEQWGMPLIAMMYPRGPKIKDEKDPEVVAHAARLGAELGADIIKTNYTGDPDTFKEVVKGCPAPIVIAGGPKTNTDEEFLQMVKDAMHAGGKGVASGRNVFQHKDVKGITRAICKIVHEDVEVKEALKEIKI","proteome":null,"gene":"aroA'","go_terms":[{"identifier":"GO:0016829","name":"lyase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004332","name":"fructose-bisphosphate aldolase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016836","name":"hydro-lyase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009073","name":"aromatic amino acid family biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"eef5f42e892995aae7b9ad95dbe411ff3160f897","counters":{"domain_architectures":38504,"entries":15,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"pfam":1,"smart":1,"cdd":1,"pirsf":1,"ncbifam":2,"panther":1,"hamap":1,"interpro":5},"proteome":0,"taxonomy":1,"similar_proteins":38504}}}