{"metadata":{"accession":"A0C6C2","id":"A0C6C2_PARTE","source_organism":{"taxId":"5888","scientificName":"Paramecium tetraurelia","fullName":"Paramecium tetraurelia"},"name":"Alpha-tubulin N-acetyltransferase","description":["Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released"],"length":249,"sequence":"MQFQFPLQKALQTSQNGISVISASNSRRNCYLDEVIDRMGEASAIAQQLKQIITTASKFYGSDQRIYLKADGKNCLGLLKVGKKNLFYRDYSGSIKEMQPLCVLDFYVHESVQRMGVGKELFEEMLKSEQIKPEKLAYDRPSQKLIGFLNKHYNLNQYVPQNNNFVIFNQYFGQGTQPIAQGRSQKYSRNSQIDQLDIMVQQISQNKTNQQQLPQQKLGYQMSTPWAIDNHTNIYNNINSQRTNVYKIN","proteome":"UP000000600","gene":"GSPATT00035468001","go_terms":[{"identifier":"GO:0019799","name":"tubulin N-acetyltransferase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0071929","name":"alpha-tubulin acetylation","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005874","name":"microtubule","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"3182cc5513ab4ebda09a8a0b7d1f84fc8921bed1","counters":{"domain_architectures":2663,"entries":8,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"profile":1,"cathgene3d":1,"pfam":1,"cdd":1,"panther":1,"hamap":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":2663}}}