{"metadata":{"accession":"A0AB33EG21","id":"A0AB33EG21_9PSED","source_organism":{"taxId":"104087","scientificName":"Pseudomonas frederiksbergensis","fullName":"Pseudomonas frederiksbergensis"},"name":"Bifunctional polymyxin resistance protein ArnA","description":["Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides"],"length":664,"sequence":"MSAKAVVFAYHDIGCAGIESLLASGFEIAAVFTHPDDPKENAFYGSVAQLCARKGIPVHAPEDANHPLWIERISKLNPDYLFSFYYRNLLSEPLLATASKGAFNLHGSLLPRYRGRAPANWVLVNGETETGVTLHRMVKRADAGAIIAQQRVAIERADTALTLHGKLRQAASDLLRDTLPALLQGKISETPQDESKATVFGRRTPADGKLVWSKPAEELFNLVRAVTQPYPGAFCAVGEHKLIVWSADVVKGNEGQAPGRVISVDPLRIACGKDSLVINAGQRNDNGLYLSGPQLANELGLVDGSVLRGAESGRAPRRTRVLILGVNGFIGNHLSERLLRDDRYEVYGLDIGSDAIERLRSHPNFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKLVRYCVKYNKRVIFPSTSEVYGMCQDANFDEDSSNLVVGPINKQRWIYSISKQLLDRVIWAYGQKGLNFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILNLVEGTPIRLFDGGEQKRCFTDIADGVEALARIIDNDNDVCNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRDNFPPFAGFRDIESKAFYGTGYQDVSHRKPSIANAKRLLDWAPTVEMKETIGNTLDFFLREAMLEIADKKR","proteome":null,"gene":"arnA","go_terms":[{"identifier":"GO:0009058","name":"biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016831","name":"carboxy-lyase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016742","name":"hydroxymethyl-, formyl- and related transferase activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"afbc655f5aa123f3b68d07693952c531c1fa295b","counters":{"domain_architectures":2057,"entries":25,"isoforms":0,"proteomes":0,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":3,"pfam":3,"cdd":2,"ncbifam":3,"hamap":1,"pirsf":1,"panther":1,"interpro":9},"proteome":0,"taxonomy":1,"similar_proteins":2057}}}