{"metadata":{"accession":"A0A9B0WL44","id":"A0A9B0WL44_CHRAS","source_organism":{"taxId":"185453","scientificName":"Chrysochloris asiatica","fullName":"Chrysochloris asiatica (Cape golden mole)"},"name":"Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma","description":["Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3"],"length":373,"sequence":"MASSSAPPATVPAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPLPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLYIVKCHGNTLLPQFLGMYRVSVDNEDCYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEGPAREEEAEGEGDCGMTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIFA","proteome":"UP000504623","gene":"PIP4K2C","go_terms":[{"identifier":"GO:0052742","name":"phosphatidylinositol kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0046488","name":"phosphatidylinositol metabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"13ff713099661d6f671208a113c5ca8bd615df76","counters":{"domain_architectures":19884,"entries":11,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"profile":1,"cathgene3d":2,"ssf":1,"smart":1,"pfam":1,"panther":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":19884}}}