{"metadata":{"accession":"A0A974HH21","id":"A0A974HH21_XENLA","source_organism":{"taxId":"8355","scientificName":"Xenopus laevis","fullName":"Xenopus laevis (African clawed frog)"},"name":"C2 Aida-type domain-containing protein","description":["Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling"],"length":309,"sequence":"MSDMNKILQKWGASLRKGTDFDSWGQLVEAIDEYQILARQLQKEAQSPANSSDFTEDQKKTIGKIATCLELRSAALQYTQSQEGFTLEDVKKLEPILSSILTFNKEFPFDVQPVPLRRILAPGEEENLEVEEEEEDGGAGVGSPDLFPARVPGAIQGTLLPRLPSEPGMTLLTIKIEKIGLKDAGQCIDPYITVSVKDLNGIDLTPVQDTPMAVRKEDTYVHFNVEIEIQKHVEKLTKGAAIFFEFKHYKPKKRFTSTKCFAFMEMDEIKSGQIVIELYKKPTDFKRKRLQLLTKKPLYLHLLQTLLKD","proteome":null,"gene":"aida.S","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"692f8b10efa2ac5bd11d6c89fe23e9a0f3923cfc","counters":{"domain_architectures":1121,"entries":11,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"ssf":1,"pfam":2,"profile":1,"panther":1,"interpro":4},"proteome":0,"taxonomy":1,"similar_proteins":1121}}}