{"metadata":{"accession":"A0A8D1WDH5","id":"A0A8D1WDH5_PIG","source_organism":{"taxId":"9823","scientificName":"Sus scrofa","fullName":"Sus scrofa (Pig)"},"name":"Peroxiredoxin-like 2A","description":["Involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway"],"length":229,"sequence":"MSFLQDPSFVTMGMWSIGAGAIGAAALALLLANTDIFLPKPQRATLDYLEDIDLKTLEKEPKTFKAKALWEKTGAVIMAVRRPGCFLCREEAADLSSLKPRLDELGVPLYAVVKEQVKNEVKDFQPYFKGEIFLDEEKKFYGPQRRKMMFMGFVRLGVWYNFFRARSGGFSGNLEGEGFVLGGVFVVGPGKQGILLEHREKEFGDKVNPVSVLEAVRKIKPHTSASEKK","proteome":null,"gene":"PRXL2A","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"443fb9c0d4ac90645217a3004302a8d616e2ab64","counters":{"domain_architectures":9787,"entries":5,"isoforms":0,"proteomes":0,"sets":2,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"cdd":1,"pfam":1,"panther":1,"interpro":1},"proteome":0,"taxonomy":1,"similar_proteins":9787}}}