{"metadata":{"accession":"A0A8C4ZIM4","id":"A0A8C4ZIM4_GADMO","source_organism":{"taxId":"8049","scientificName":"Gadus morhua","fullName":"Gadus morhua (Atlantic cod)"},"name":"GDNF family receptor alpha-1","description":["Coreceptor for GDNF, a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. GDNF-binding leads to autophosphorylation and activation of the RET receptor"],"length":477,"sequence":"MILATFLIVFSYLDMISTLKGDGTPSRSASRLDCVKASEQCLKEYTCSTKYRTMRQCVAGRESNFSAVTGTEAQGECRSAIEAMKQSPLYNCRCRRGMKKEKNCLRIFWSIFESLQGNDLLEDSPYEPVNSRLSDIFRLAPIISGEPASAKENSCLSAAKACNLNDTCKRYRSAYINPCTSRVSVSEVCNKRKCHKALRQFFDKVPAKHSYGMLYCSCPAGDQSACEERRRQTIVPICSYEDRDKPNCMSLQNACKTNYICRSRLADFISNCQPEAHSVSGCLRENYADCLLSYSGLIGTVMTPNYQRALGLSPSPWCDCASSGNNRAECDKFSDLFTTNRCLRNAIQAFGNGTDVGVWQPQPPLRSTTAQPGTSRRGKEPSGHGLDPLTHDNTLGLEADALYSFCGSLQAQKLESNATADTALCVNSKQDELADSRSVPRSSSSGLPLPRFPVLLPPVVLTFMPFLYPPPGLRPGP","proteome":"UP000694546","gene":"gfra1b","go_terms":[{"identifier":"GO:0038023","name":"signaling receptor activity","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"8c8e00da0dd3913a1b9d4fb34243f0db26f04abb","counters":{"domain_architectures":3735,"entries":13,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"smart":1,"ssf":1,"cathgene3d":1,"pirsf":1,"panther":1,"prints":2,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":3735}}}