{"metadata":{"accession":"A0A8C1FJ72","id":"A0A8C1FJ72_CYPCA","source_organism":{"taxId":"630221","scientificName":"Cyprinus carpio carpio","fullName":"Cyprinus carpio carpio"},"name":"NEDD8-conjugating enzyme UBC12","description":["Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation"],"length":178,"sequence":"MQQKKDEESAGGARAGAGGKKASAAQLRIQKDINELNLPKTCEIVFPDQDDLLNFKLIISPDEGFYKGGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQTNRRLFEQNVQRSLRGGYVGATYFERCLK","proteome":"UP001108240","gene":null,"go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"96b2a7d582dea26386e8f982d2fd40014d2b06f9","counters":{"domain_architectures":122920,"entries":12,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cathgene3d":1,"cdd":1,"profile":1,"smart":1,"pfam":1,"panther":1,"prosite":1,"interpro":4},"proteome":1,"taxonomy":1,"similar_proteins":122920}}}