{"metadata":{"accession":"A0A7K7CDM1","id":"A0A7K7CDM1_APHCE","source_organism":{"taxId":"39617","scientificName":"Aphelocoma coerulescens","fullName":"Aphelocoma coerulescens (Florida scrub-jay)"},"name":"UDP-glucose 4-epimerase","description":["Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids"],"length":375,"sequence":"QGAMAEKILVTGGAGYIGSHCVLELLQAGYVPVVIDNFHNAIRGSEELPESLRRVQDIVHQPVLFQELDITDEAALQELFRKHRFSAVMHFAGLKAVGESVQKPLEYYRVNLTGTIRLLETMKAHGVRNIVFSSSATVYGDPKYLPLDEKHPVGGCTNPYGKSKFFIEEMIRDLCKAERDWNAVLLRYFNPIGAHESGMIGEDPQGIPNNLMPYVAQVAVGRREFLSVFGNDYKTDDGTGASRDGRNFRFPNPWLHPGLCPHPLHPPGVRDYIHVVDLAKGHIAALKKLKENCGCKVYNLGTGTGYSVLQMVRAMEKASGREIKYQITARREGDVASCYADPALAERELGWKAAFGLDKMCKGIPSLARWALPDP","proteome":"UP000575874","gene":"Gale","go_terms":[{"identifier":"GO:0003978","name":"UDP-glucose 4-epimerase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006012","name":"galactose metabolic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":true,"in_alphafold":true,"in_bfvd":false,"ida_accession":"d2eb2fbd63cfbf5e01dcf985088804d0b8dd1eb2","counters":{"domain_architectures":564,"entries":11,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cdd":1,"cathgene3d":2,"pfam":1,"panther":1,"ncbifam":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":564}}}