{"metadata":{"accession":"A0A7J8CSS4","id":"A0A7J8CSS4_MOLMO","source_organism":{"taxId":"27622","scientificName":"Molossus molossus","fullName":"Molossus molossus (Pallas' mastiff bat)"},"name":"Neutrophil cytosol factor 2","description":["Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox"],"length":480,"sequence":"MSLAEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCVHTILENWAAAEKAFSRTINRDKHLAVAYFQRGMLYHRLQKYDSAITDLKEALTQLRGNQLIDYKILGLQFKLFACEKQKLYEPVVVPVGRLFRPNERQVAQLEKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETPEELQVMPGNIVFVLKKGNDNWATVIFNGQKGLVPCNYLEPVSLRIHPQQQSQEEASPESEIPDPPISSAPGRPQLPPGQKEKEESKEVKLSVPMLYTLKVHYKYTVVMETQPGLPYSQVRDMVSKKLELLPEHTKLSYRPGDSRDLVPLSEDSMKDAWGQAKNYCLTLWCEHTVGDQGFPEEPEESEKSDASGQTPEPPLKEGSRVVALFSYQAAQPEDLEFLEGDIIQVVSMVNDEWLEGTCKGKFGIFPKAFVEQAAAGLDSTPRGV","proteome":"UP000550707","gene":"HJG59_012864","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"3ef0bd189f43de2d19ed7e2022a434a6dc6a2850","counters":{"domain_architectures":266,"entries":29,"isoforms":0,"proteomes":1,"sets":5,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"ssf":3,"smart":3,"profile":3,"pfam":3,"cdd":2,"panther":1,"prints":2,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":266}}}