{"metadata":{"accession":"A0A6P6F4H6","id":"A0A6P6F4H6_OCTDE","source_organism":{"taxId":"10160","scientificName":"Octodon degus","fullName":"Octodon degus (Degu)"},"name":"Sodium-coupled neutral amino acid symporter 2","description":["Symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane. The transport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier. May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta. Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate. Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development"],"length":427,"sequence":"MQMSTLKTRTFYLNRIWGRRSMKQTLILLTFVSIFSLYSVHLLLKTASEGGSLLYEQLGHKAFGMLGKLAASGSITIQNIGAMSSYLFIVKYELPLVIKALMNIEDTNGLWYLNGDYLVLLVSLMLILPLSLLRNLGYLGYTSGLSLLCMVFFLIVVICKKFQIPCPMEVALLMNETVNTTLTQSAELASTGGLNATVADSCRPRYFIFNSQTVYAVPILTFSFVCHPAILPIYEELKGRSQRRMMNVSKISFFAMFLMYLLAALFGYLTFYGRVESELLHTYSTVVGTDIILLIVRLAVLVAVTLTVPVAVFPIRSSITHLLCPTKDFSWWRHSLITVSILVFTNLLVIFVPSIKDIFGFIGASAAAMLIFILPSAFYIKLVKKERMKSVQKIGALLFLLSGILVMIGSMALIVLDWVHNASNGHR","proteome":"UP000515203","gene":"Slc38a2","go_terms":null,"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"563bf97a90fdce69b83f48705e7686854a329061","counters":{"domain_architectures":91119,"entries":3,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"pfam":1,"panther":1,"interpro":1},"proteome":1,"taxonomy":1,"similar_proteins":91119}}}