{"metadata":{"accession":"A0A6P6CW49","id":"A0A6P6CW49_PTEVA","source_organism":{"taxId":"132908","scientificName":"Pteropus vampyrus","fullName":"Pteropus vampyrus (Large flying fox)"},"name":"Delta(14)-sterol reductase TM7SF2","description":["Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis"],"length":317,"sequence":"MLLPLAFVATLTAFIFSLLLYLKALLAPTSTLAPGGNSGNPIYDFFLGRELNPRIRSFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWQEEAVLTTMDITHDGFGFMLAFGDLAWVPFTYSLQAQFLLYHPQPLGLPMASVICLINAFGFYIFRGANSQKNTFRKNPSDPRVADLETIPTATGRQLLVSGWWGMVRHPNYLGDLIMALAWSLPCGEWLGWGHIRVRGRDGVVTAGYPVWVWNGERGCTPVEGVVREPGPDSGCGWGRCRRQPSAASTLSWSLASLRLSADAVSH","proteome":"UP000515202","gene":"TM7SF2","go_terms":[{"identifier":"GO:0016628","name":"oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016126","name":"sterol biosynthetic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"9a69035bc8c6d4031bf06ea0caf3992496028c64","counters":{"domain_architectures":10044,"entries":6,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"panther":1,"pfam":1,"prosite":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":10044}}}