{"metadata":{"accession":"A0A6J3CSS6","id":"A0A6J3CSS6_AYTFU","source_organism":{"taxId":"219594","scientificName":"Aythya fuligula","fullName":"Aythya fuligula (Tufted duck)"},"name":"General transcription and DNA repair factor IIH subunit TFB5","description":["In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape"],"length":71,"sequence":"MVNVLKGVLIECDPAMKQFLLYLDESNALGKKFIIQDLDETHVFVLAELVNFLQERVGELMDQNSFPITQK","proteome":"UP000504639","gene":"GTF2H5","go_terms":[{"identifier":"GO:0006289","name":"nucleotide-excision repair","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0006367","name":"transcription initiation at RNA polymerase II promoter","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0000439","name":"transcription factor TFIIH core complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"178cb7c84e71b5a779d05632e12160bcd8707d09","counters":{"domain_architectures":3136,"entries":7,"isoforms":0,"proteomes":1,"sets":0,"structures":0,"taxa":1,"dbEntries":{"smart":1,"cathgene3d":1,"ssf":1,"pfam":1,"panther":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":3136}}}