{"metadata":{"accession":"A0A6J2W9W8","id":"A0A6J2W9W8_CHACN","source_organism":{"taxId":"29144","scientificName":"Chanos chanos","fullName":"Chanos chanos (Milkfish)"},"name":"5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial","description":["GTPase component of the GTPBP3-MTO1 complex that catalyzes the 5-taurinomethyluridine (taum(5)U) modification at the 34th wobble position (U34) of mitochondrial tRNAs (mt-tRNAs), which plays a role in mt-tRNA decoding and mitochondrial translation. Taum(5)U formation on mammalian mt-tRNA requires the presence of both GTPBP3-mediated GTPase activity and MTO1 catalytic activity"],"length":505,"sequence":"MYFVAGELWRIFAPFVPRNVLQRRFCSSSLAAEGTIFALSSGQGRCGVAVIRVSGPDSAHALRTLTGRTRDLLTPRVAHLCSIRHPRSHELLDRGLVLWFPGPHSFTGEDSAEFHVHGGPAVISGVLQALGSLAGLRPAEAGEFTRRAFHAGKLDLTEVEGLGDLIHAETEAQRRQALRQMAGDLGRLYSNWSQQLKTCLAHAEAFIDFGEDELIEDGLLNQVDSTVSQLRVEIQKHLHDNRRGEMLRSGVQLVLAGATNAGKSSLLNIICQRPAAIVSPVAGTTRDVVETHVDIGGFPVVLSDTAGLRDTEDIVEREGVRRARLTVENADLTLVIIDSALLPPDPHAAPDFLRDHLRNTLSADKDLAAAQNCLMVLNKSDLLTREQVSSICRVLNQTPRLPSACFLSCLTGHGLEEFLTLLRSKVTSLCGDPLVGSPSLTQARHRTHLEKAVKALGQYQQYREVDLALAAEGLRLGLTSLGRITGRVDPEEILDVIFRDFCIGK","proteome":"UP000504632","gene":"gtpbp3","go_terms":[{"identifier":"GO:0005515","name":"protein binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005525","name":"GTP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003924","name":"GTPase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006400","name":"tRNA modification","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"164d696ab196da12f9a745cf3fc980c3859f858f","counters":{"domain_architectures":23848,"entries":25,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":3,"cdd":2,"ssf":2,"profile":1,"ncbifam":3,"panther":1,"hamap":1,"pfam":3,"interpro":9},"proteome":1,"taxonomy":1,"similar_proteins":23848}}}