{"metadata":{"accession":"A0A6J2F5D1","id":"A0A6J2F5D1_ZALCA","source_organism":{"taxId":"9704","scientificName":"Zalophus californianus","fullName":"Zalophus californianus (California sealion)"},"name":"N-terminal EF-hand calcium-binding protein 2","description":["May act as a signaling scaffold protein that senses intracellular calcium. Can modulate ligand-induced internalization of ADORA2A and coupling efficiency of mGluR5/GRM5; for both receptors may regulate signaling activity such as promoting MAPK1/3 (ERK1/2) activation"],"length":406,"sequence":"MCERAARLCRAGAHRLLREPPPQSRALGGLLRWVGARMGEPRAPLAPDAHDAPAADPSPGPGPGSPRGGTAVILDIFRRADKNDDGKLSLEEFQLFFADGVLNEKELEDLFHTIDSDNTNHVDTKELCDYFVDHMGDYEDVLASLETLNHSVLKAMGYTKKVYEGGSNVDQFVTRFLLKETANQIQSLLSSVESAVEAIEEQTSQIRQNHSKPSHGVVETWSGSAAPPHAPNPKLGASEQGKSLPSGTVDPKEEGLEAQISRLAELIGRLESKTLWFDLQQRLSDEEGTNMHLQLVRQEMAVCPEQLSEFVDSLRQYLRGTAGARNCFHIAAVRLADGFTFVVYEFWETEEEWRRHLLSPVCKAFRHVKVDTLSQPEALSRILVPETLVYKLSFQYTSGQECIFPV","proteome":"UP000515165","gene":"NECAB2","go_terms":[{"identifier":"GO:0005509","name":"calcium ion binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":4,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"79d8bdb9c2e4a5d6ae040c73a18a023bbf38eeda","counters":{"domain_architectures":438,"entries":18,"isoforms":0,"proteomes":1,"sets":3,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":2,"profile":2,"ssf":2,"smart":1,"pfam":2,"cdd":1,"panther":1,"prosite":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":438}}}