{"metadata":{"accession":"A0A6J1VDB2","id":"A0A6J1VDB2_9SAUR","source_organism":{"taxId":"8663","scientificName":"Notechis scutatus","fullName":"Notechis scutatus (mainland tiger snake)"},"name":"Biliverdin reductase A","description":["Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IXalpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. Does not reduce bilirubin IXbeta. Uses the reactants NADH or NADPH depending on the pH; NADH is used at the acidic pH range (6-6.9) and NADPH at the alkaline range (8.5-8.7). NADPH, however, is the probable reactant in biological systems"],"length":296,"sequence":"MFGTVVIGIGIAGSVRIRDLLNPLPSSPAEHLKLLGFVSRRSLNEVYQVKQISLQEALDNPEIHAAIISTDNQNHTESVRKFLEAGKHVLVEYPLALSAKIAHEVWELAELKDKILHVEHIELLTEEYKQLKKEVSGKELVKGTLHFTGGPLDERYSGFPSFSGIARLTWLVDLFGDLTVTSATREQQKENNYFRMTVHFQTANKRPLTWIEERGPGMKRDKKINFCFKNGCLECLPEAPRSPVGLFMQDLIIFAKKLLGQIPKEELTAEKKRILLCLSLAEEIQMHCEAPSTFYS","proteome":"UP000504612","gene":"BLVRA","go_terms":[{"identifier":"GO:0000166","name":"nucleotide binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0004074","name":"biliverdin reductase [NAD(P)H] activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0008270","name":"zinc ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0042167","name":"heme catabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005737","name":"cytoplasm","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"807cb7f491ce4525417f61aaec49006ab219d444","counters":{"domain_architectures":998,"entries":13,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":2,"cathgene3d":2,"pfam":2,"pirsf":1,"panther":1,"interpro":5},"proteome":1,"taxonomy":1,"similar_proteins":998}}}